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Biotinylated Anti-Trastuzumab ADA Antibody, Mouse IgG1 (6F2F7-2)

  • Source

    Biotinylated Anti-Trastuzumab ADA Antibody, Mouse IgG1 (6F2F7-2) is a Mouse monoclonal antibody recombinantly expressed from HEK293 cells.

  • Clone

    6F2F7-2

  • Species

    Mouse

  • Isotype

    Mouse IgG1 | Mouse Kappa

  • Conjugate

    Biotin

  • Antibody Type

    Recombinant Monoclonal

  • Reactivity

    Human

  • Specificity

    This product is a specific antibody specifically reacts with Trastuzumab ADA.

  • Application
    ApplicationRecommended Usage
    ELISA0.5-125 ng/mL
  • Purity

    >90% as determined by SDS-PAGE.

  • Purification

    Protein A purified/ Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Trastuzumab ADA SDS-PAGE

Biotinylated Anti-Trastuzumab ADA Antibody, Mouse IgG1 (6F2F7-2) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-ELISA
 Trastuzumab ADA ELISA

Immobilized Trastuzumab Biosimilar at 1 μg/mL (100 μL/well) can bind Biotinylated Anti-Trastuzumab ADA Antibody, Mouse IgG1 (6F2F7-2) (Cat. No. TRA-BLY5b) with a linear range of 0.5-16 ng/mL (QC tested).

  • Background
    Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.
  • Clinical and Translational Updates

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ETD of in-stock products: 4 business days

価格(JPY) : 98,000

価格(JPY) : 386,400

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