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Your Position: ホーム > Tau

Tau

概要

Name:Microtubule-associated protein tau
Target Synonym:MAPT,MTBT1,Paired helical filament-tau,MAPTL,Microtubule Associated Protein Tau,G Protein Beta1/Gamma2 Subunit-Interacting Factor 1,Protein Phosphatase 1, Regulatory Subunit 103,Neurofibrillary Tangle Protein,PHF-Tau,TAU,Microtubule-Associated Protein Tau, Isoform 4,Microtubule-Associated Protein Tau,PPP1R103,FTDP-17,MTBT2,DDPAC,MSTD,PPND,tau Proteins,MGC138549,FLJ31424
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:34
Lastest Research Phase:Approved

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製造番号 種類 製品説明 構造 純度 特徴
TAU-H5113 Human Human Tau-441 K18 (P301L) Pre-formed Fibrils Protein, Tag Free
TAU-H5113-structure
TAU-H5113-sds
TAU-H5146 Human Human Tau-441 K18 Pre-formed Fibrils Protein, His Tag
TAU-H5146-structure
TAU-H5146-sds
TAU-H5147 Human Human Tau-441 GSK-3beta-phosphorylated protein, His Tag
TAU-H5147-structure
TAU-H5147-sds
CHEK-ATP087 Human HEK293/Human Tau-K18 (GFP) Stable Cell Line
TAU-H5118 Human Human Tau-441 (K18, P301L) Protein, Tag Free (MALS verified)
TAU-H5118-structure
TAU-H5118-sds
TAU-H5117 Human Human Tau-441 / 2N4R Protein, Tag Free (MALS verified)
TAU-H5117-structure
TAU-H5117-sds
TAU-H5115 Human Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free
TAU-H5115-structure
TAU-H5115-sds
TAU-H5145 Human Human Tau-441 / 2N4R (P301S) Protein, His Tag (MALS verified)
TAU-H5145-structure
TAU-H5145-sds
TAU-H5144 Human Human Tau-441 / 2N4R (P301L) Protein, His Tag
TAU-H5144-structure
TAU-H5144-sds
TAU-H5143 Human Human Tau-410 / 2N3R Protein, His Tag (MALS verified)
TAU-H5143-structure
TAU-H5143-sds
TAU-H51H4 Human Human Tau-441 / 2N4R (241-380) Protein, His Tag (MALS verified)
TAU-H51H4-structure
TAU-H51H4-sds
TAU-H51H5 Human Human Tau-441 / 2N4R (273-380) Protein, His Tag (MALS verified)
TAU-H51H5-structure
TAU-H51H5-sds
TAU-H51H3 Human Human Tau-441 / 2N4R Protein, His Tag
TAU-H51H3-structure
TAU-H51H3-sds
ACRO Quality

生物活性データの一部

CHEK-ATP087-Cell-based assay
Tau FACS

FACS analysis of Tau-K18 (GFP) on HEK293/Human Tau-K18 (GFP) Stable Cell Line.
HEK293/Human Tau-K18 (GFP) Stable Cell Line was red line, negative control HEK293 cells was grey line (QC tested).

Protocol
TAU-H5117-ELISA
Tau ELISA

Immobilized Human Tau-441, Tag Free (Cat. No. TAU-H5117) at 1 μg/mL (100 μL/well) can bind Tau Monoclonal Antibody with a linear range of 0.4-6 ng/mL (QC tested).

Protocol
TAU-H5118-MALS-HPLC
Tau MALS images

The purity of Human Tau-441 (K18, P301L) Protein, Tag Free (Cat. No. TAU-H5118) is more than 85% and the molecular weight of this protein is around 12-18 kDa verified by SEC-MALS.

Synonym Name

DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU

Background

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Clinical and Translational Updates

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