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Matrix Metalloproteinases

Matrix Metalloproteinases
Product Features
High Purity (>90%)
QC -verified High Enzymatic Activity
QC-verified batch-to-batch consistency
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Research Applications
Immunization
Antibody Screening
Functional Studies
Drug Hit-Lead Discovery
Enzyme Research
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that play a significant role in degrading various substrates within the cell and in the extracellular matrix. This includes substrates such as:
• Myelin and other extracellular matrix proteins.
• Cytokines & other growth factors
• Cell adhesion-associated molecules
As such, MMPs are an integral part of enabling cell migration, playing a role in physiological processes including ECM metabolism, cell migration, tissue repair, tissue remodeling, and many others. Different MMPs are expressed in different tissue types, with aberrant expression closely associated with the onset of diseases, including inflammatory, cardiovascular, and cancer diseases.
We now offer a wide range of highly active MMP recombinant proteins, including MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 and MMP-10.
MMP Family Product List
MoleculeCat. No.Product DescriptionPreorder/Order
Related Products
Purity Data
The purity of Human MMP-9

The purity of Human MMP-9, His Tag (Cat. No. MM9-H5229) is more than 90% and the molecular weight of this protein is around 50-70 kDa verified by SEC-MALS. The purity of the protein is greater than 95% verified by SDS-PAGE.

Enzyme Activity Data
Cat. No.Human MMP-9 Protein, His Tag (active enzyme) (MALS verified)
SubstrateMca-PLGL-Dpa-AR-NH2
Enzyme Activity
(pmol/min/μg)
ACRO product
(Cat. No.:MM9-H5229
Competitor R
>3,000(QC tested)>1,300
Cat. No.Human MMP-7 / PUMP1 Protein, His Tag (active enzyme)
SubstrateMca-PLGL-Dpa-AR-NH2
Enzyme Activity
(pmol/min/μg)
ACRO product
(Cat. No.:MM7-H5249
Competitor R
>600 (QC tested)>600
Cat. No.Human MMP-3 Protein, His Tag (active enzyme, MALS verified)
SubstrateMca-RPKPVE-Nval-WRK(Dnp)-NH2
Enzyme Activity
(pmol/min/μg)
ACRO product
(Cat. No.:MM3-H52H3
Competitor R
>422(QC tested)>150

(Activation description: The proenzyme needs to be activated by APMA for an activated form)

ACRO Quality

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