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Mouse ROR2 / NTRKR2 Protein, His Tag (MALS verified)

  • Synonym
    ROR2,NTRKR2
  • Source
    Mouse ROR2 Protein, His Tag(RO2-M52H3) is expressed from human 293 cells (HEK293). It contains AA Glu 34 - Gly 403 (Accession # Q9Z138-1).
    Predicted N-terminus: Glu 34
  • Molecular Characterization
    ROR2 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 43.1 kDa. The protein migrates as 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
ROR2 SDS-PAGE

Mouse ROR2 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
ROR2 MALS images

The purity of Mouse ROR2 Protein, His Tag (Cat. No. RO2-M52H3) is more than 85% and the molecular weight of this protein is around 45-65 kDa verified by SEC-MALS.

  • Background
    Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.
  • Clinical and Translational Updates

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