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Your Position: ホーム > Beads > uPAR > MBS-K076

Human uPAR-coupled Magnetic Beads

ItemsSize (2mg)Size(2mg X 5)
Particle size2 μm2 μm
Physical appearancePowder mixturePowder mixture
Amount of Coupled Protein≈1371pmol(48μg) uPAR protein/mg beads≈1371pmol(48μg) uPAR protein/mg beads
Capacity>277pmol (20μg) Anti-uPAR Ab/mg beads>277pmol (20μg) Anti-uPAR Ab/mg beads
FormulationPBS, pH7.4,with 10% TrehalosePBS, pH7.4,with 10% Trehalose
Reconstitution2mL ultrapure water (1 mg beads/mL)2mL ultrapure water (1 mg beads/mL)
  • Background
    Tumors are the result of uncontrolled proliferation of cells in different organs. Tumor development is a multistage process, that includes the generation of primary tumors, separation of tumors from primary sites, degradation of extracellular matrix (ECM), and distant metastasis of tumors. A variety of genes play important roles in the development of tumors, including the cell surface receptor urokinase-type plasminogen activator receptor (uPAR). uPAR is highly expressed in a variety of tumor cells, and a variety of signals regulated by uPAR play significant roles in tumor cell proliferation and metastasis, tumor-related glycolysis, the tumor microenvironment and angiogenesis. Studies have found that some specific drugs and antibodies have unique inhibitory effects on uPAR.
  • Application
    This product is intended for immunocapture, biopanning and flow cytometry. This is a non-sterile product.
    *The Isotype control (Cat. No. SMB-B01) is sold separately.
  • Reconstitution

    See Certificate of Analysis (CoA) for detailed instruction.

  • Storage
    Upon receipt, please store the Beads at -20°C. The shelf life is 1 year at -20 °C.Please avoid more than 3 freeze-thaw cycles once reconstitution, immediate use after reconstitution is highly recommended.
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

Typical Data
 uPAR TYPICAL DATA

Immobilized 48.8μg Biotinylated Human uPAR protein to 1mg Beads can bind the Anti-uPAR Antibody with an EC50 0.52 μg/mL (QC tested).

  • Clinical and Translational Updates

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ETD of in-stock products: 4 business days

価格(JPY) : 224,000

価格(JPY) : 700,000

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医薬品開発状況

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:5 Details
  • Latest Research Phase:Phase 2 Clinical

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