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Your Position: ホーム > Protein > Galectin-4 > GA4-H5246

Human Galectin-4 / LGALS4 / L36LBP Protein, His Tag

  • Synonym
    LGALS4,L36LBP,Gal-4,Antigen NY-CO-27,Lactose-binding lectin 4
  • Source
    Human Galectin-4, His Tag(GA4-H5246) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ile 323 (Accession # P56470-1).
    Predicted N-terminus: His
  • Molecular Characterization
    Galectin-4 Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 38.1 kDa. The protein migrates as 40-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM HEPES, 150 mM NaCl, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Galectin-4 SDS-PAGE

Human Galectin-4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.
  • Clinical and Translational Updates

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