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Your Position: ホーム > VEGF110

VEGF110

概要

Name:Vascular endothelial growth factor A
Target Synonym:Vascular Endothelial Growth Factor,VEGF-A,MVCD1,Vascular endothelial growth factor A,VEGF,VEGFA,VPF,Vascular Endothelial Growth Factor A165,Vascular permeability factor,Vascular Endothelial Growth Factor A121
Number of Launched Drugs:40
Number of Drugs in Clinical Trials:63
Lastest Research Phase:Approved

ライセンス

Project Name Modality Therapeutic Area Indications Stage Right Available
PD-1+VEGF bsAb Bispecific antibody Oncology/Cancer Solid tumor Phase I Global  (except China)

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製造番号 種類 製品説明 構造 純度 特徴
VE0-H52H3 Human Human VEGF110 Protein, His Tag (MALS verified)
VE0-H52H3-structure
VE0-H52H3-sds
VE0-H5212 Human Human VEGF110 Protein, premium grade
VE0-H5212-structure
VE0-H5212-sds
ACRO Quality

生物活性データの一部

VE0-H5212-Cell-based assay
VEGF110 CELL

Human VEGF110 Protein, premium grade (Cat. No. VE0-H5212) stimulates proliferation of human umbilical vein endothelial cells (HUVEC). The EC50 for this effect is 5.06-11.59 ng/mL (Routinely tested).

Protocol
VE0-H52H3-SPR
VEGF110 SPR

Human VEGFR1/R2 captured on Protein A Chip can bind Human VEGF110 Protein, His Tag (Cat. No. VE0-H52H3) with an affinity constant of 13.8 pM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
VE0-H5212-ELISA
VEGF110 ELISA

Immobilized Human VEGF110 Protein, premium grade (Cat. No. VE0-H5212) at 0.05 μg/mL (100 μL/well) can bind Human VEGF R1 Protein, His Tag (Cat. No. VE1-H52H9) with a linear range of 2-16 ng/mL (QC tested).

Protocol

Synonym Name

RP1-261G23.1,MGC70609,MVCD1,VEGFA,VPF

Background

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, and is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. Alternatively spliced isoforms of 110,121,145,165,183,189 and 206 amino acids in length are expressed in humans.

Clinical and Translational Updates

公開薬物情報

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Ranibizumab biosimilar (Intas Biopharmaceuticals) Approved Intas Biopharmaceuticals Razumab India Macular Degeneration Intas Biopharmaceuticals 2015-01-01 Macular Degeneration Details
Bevacizumab biosimilar (Dr. Reddy's Laboratories) Approved Dr Reddy's Laboratories Ltd Versavo India Glioblastoma; Carcinoma, Renal Cell; Peritoneal Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Non-Small-Cell Lung; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms Dr Reddy's Laboratories Ltd 2019-08-19 Carcinoma, Renal Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Breast Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Bevacizumab biosimilar (Zydus Cadila) Approved Zydus Cadila Bryxta India Carcinoma, Non-Small-Cell Lung Zydus Cadila 2017-01-01 Carcinoma, Renal Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Colorectal Neoplasms; Peritoneal Neoplasms; Metastatic breast cancer; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar(Apotex ) Approved Apotex Inc BAMBEVI Canada Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Glioblastoma; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Apotex Inc 2021-09-23 Carcinoma, Ovarian Epithelial; Glioblastoma; Peritoneal Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Reliance Life Sciences) R-TPR-023 Approved Reliance Life Sciences BevaciRel India Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Glioblastoma; Carcinoma, Renal Cell; Uterine Cervical Neoplasms; Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Fallopian Tube Neoplasms Reliance Life Sciences Pvt Ltd 2016-06-13 Carcinoma, Renal Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Bevacizumab biosimilar (AryoGen Biopharma) BE1040V Approved Aryogen Biopharma Stivant Iran Glioblastoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Colorectal Neoplasms; Uterine Cervical Neoplasms; Metastatic breast cancer; Peritoneal Neoplasms; Fallopian Tube Neoplasms Aryogen Biopharma 2019-06-01 Carcinoma, Renal Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Colorectal Neoplasms; Peritoneal Neoplasms; Metastatic breast cancer; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Bevacizumab biosimilar (Intas Pharmaceuticals) INTP-24 Approved Intas Biopharmaceuticals Bevatas India Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Uterine Cervical Neoplasms; Glioblastoma; Breast Neoplasms Intas Biopharmaceuticals 2017-10-04 Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Glioblastoma; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Bevacizumab biosimilar (Biocad) BCD-021 Approved Biocad Avegra Russian Federation Carcinoma, Ovarian Epithelial; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Breast Neoplasms; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Uterine Cervical Neoplasms; Glioblastoma; Carcinoma, Renal Cell Biocad 2015-11-25 Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Glioblastoma; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Bevacizumab biosimilar (Elea) Approved Laboratorio Elea Phoenix Sa Lumiere Argentina Macular Degeneration Laboratorio Elea Phoenix Sa 2018-04-26 Macular Degeneration Details
Ranibizumab biosimilar (Senju) GBS-007; OT-701; SJP-0133 Approved Senju Pharmaceutical Co Ltd Japan Macular Degeneration Senju Pharmaceutical Co Ltd 2021-09-27 Macular Degeneration Details
Bevacizumab biosimilar (Hetero Drugs) Approved Hetero Drugs Ltd Cizumab India Colorectal Neoplasms Hetero Drugs Ltd 2016-06-27 Colorectal Neoplasms Details
Bevacizumab biosimilar (Biocon/Mylan) MYL-1402O Approved Biocon Ltd KRABEVA, Abevmy, Lextemy EU Carcinoma, Non-Small-Cell Lung; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Peritoneal Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial Mylan Ire Healthcare Ltd 2017-11-27 Ovarian Neoplasms; Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Brain Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Pfizer) PF-6439535; PF-06439535 Approved Pfizer Inc Zirabev United States Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Ovarian Epithelial Pfizer Inc 2019-02-14 Carcinoma, Renal Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Neovasculgen PI-VEGF165 Approved Human Stem Cells Institute Neovasculgen Russian Federation Peripheral Arterial Disease Human Stem Cells Institute 2011-12-07 Peripheral Arterial Disease; Peripheral Nerve Injuries Details
Bevacizumab biosimilar (Allergan/Amgen) ABP-215 Approved Amgen Inc Mvasi United States Fallopian Tube Neoplasms; Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms Amgen Inc 2017-09-14 Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Glioblastoma; Breast Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Bevacizumab biosimilar (Qilu Pharma) QL-1101 Approved Qilu Pharmaceutical Co Ltd 安可达 Mainland China Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms Qilu Pharmaceutical Co Ltd 2019-12-06 Colorectal Neoplasms; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Celltrion) CTP-16; CT-16; CT-P16 Approved Celltrion Inc Vegzelma United States Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Glioblastoma; Carcinoma, Renal Cell Celltrion Inc 2022-08-17 Ovarian Neoplasms; Carcinoma, Renal Cell; Adenocarcinoma of Lung; Carcinoma, Ovarian Epithelial; Glioblastoma; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Ziv-aflibercept BAY-865321; AVE-0005 Approved Regeneron Pharmaceuticals Inc, Sanofi Zaltrap Japan Colorectal Neoplasms Sanofi 2012-08-03 Lymphoma; Urethral Neoplasms; Breast Neoplasms; Brain Neoplasms; Colorectal Neoplasms; Carcinoma, Mucoepidermoid; Genital Neoplasms, Female; Gliosarcoma; Astrocytoma; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Ureteral Neoplasms; Peritoneal Neoplasms; Lung Neoplasms; Prostatic Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Neuroendocrine; Uterine Neoplasms; Endometrial Neoplasms; Glioma; Lymphoma, Non-Hodgkin; Carcinoma, Squamous Cell; Thyroid Neoplasms; Retinal Vein Occlusion; Neoplasm Metastasis; Melanoma; Carcinoma, Non-Small-Cell Lung; Glioblastoma; Leiomyosarcoma; Solid tumours; Multiple Endocrine Neoplasia Type 1; Leukemia; Rectal Neoplasms; Carcinoma; Carcinoma, Renal Cell; Carcinoid Tumor; Colonic Neoplasms; Neoplasms; Carcinoma, Ovarian Epithelial; Pancreatic Neoplasms; Ovarian Neoplasms; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Myeloproliferative Disorders; Carcinoma, Papillary; Carcinoma, Transitional Cell; Small Cell Lung Carcinoma; Ascites; Lung Diseases; Adenoc Details
Bevacizumab biosimilar (Jiangsu Hengrui Medicine) BP-102 Approved Jiangsu Hengrui Medicine Co Ltd 艾瑞妥 Mainland China Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Suzhou Suncadia Biopharmaceuticals Co Ltd 2021-06-22 Solid tumours; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Conbercept FP-3; KH-902 Approved Chengdu Kanghong Biotechnologies Co Ltd 朗沐, Langmu Mainland China Macular Degeneration Chengdu Kanghong Biotechnologies Co Ltd 2013-11-27 Macular Edema; Vision Disorders; Diabetic macular oedema; Wet Macular Degeneration; Retinoblastoma; Hemangioma; Uveitis; Corneal Neovascularization; Macular Degeneration; Choroidal Neovascularization; Diabetes Mellitus; Retinal Vein Occlusion Details
Aflibercept BAT-86-5321; BAY-865321 Approved Regeneron Pharmaceuticals Inc, Bayer AG Eylea Japan Retinopathy of Prematurity Bayer Yakuhin Ltd 2011-11-18 Diabetic macular oedema; Corneal Neovascularization; Choroidal Neovascularization; Retinal Vein Occlusion; Carcinoma, Non-Small-Cell Lung; Diabetic Retinopathy; Macular Degeneration; Retinopathy of Prematurity; Neoplasm Metastasis; Lymphoma, Non-Hodgkin; Retinal Degeneration; Eye Diseases; Vitreous Hemorrhage; Diabetes Complications; Colorectal Neoplasms; Retinitis Pigmentosa; Diabetes Mellitus, Type 1; Wet Macular Degeneration; Prostatic Neoplasms; Retinal Diseases; Multiple Myeloma; Myopia, Degenerative; Central Serous Chorioretinopathy; Colonic Neoplasms; Neoplasms; Choroid Diseases; Rectal Neoplasms; Glaucoma, Neovascular; Macular Edema; Diabetes Mellitus, Type 2; Cataract Details
Bevacizumab G180CU; RO-4876646; RG-435; NSC-704865; G180CL; R-435; G180DL Approved Genentech Inc 安维汀, Avastin Mainland China Carcinoma, Hepatocellular Shanghai Roche Pharmaceuticals Ltd 2004-02-26 Solid tumours; Pterygium; HIV Infections; Ependymoma; Ovarian Neoplasms; Kidney Neoplasms; Leiomyosarcoma; Fibrosarcoma; Liver Neoplasms; Epistaxis; Telangiectasia, Hereditary Hemorrhagic; Arteriovenous Malformations; Leukemia; Head and Neck Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Macular Edema; Abdominal Neoplasms; Telangiectasis; Rectal Neoplasms; Carcinoma, Renal Cell; Meningeal Carcinomatosis; Hemangioblastoma; Esophageal Neoplasms; Anaplasia; Vaginal Neoplasms; Carcinoma; Esthesioneuroblastoma, Olfactory; Carcinoma, Basal Cell; Carcinoid Tumor; Diabetes Mellitus, Type 2; Granuloma, Lethal Midline; Squamous Cell Carcinoma of Head and Neck; Salivary Gland Neoplasms; Nasopharyngeal Neoplasms; Central Serous Chorioretinopathy; Adenocarcinoma of Lung; Glioblastoma; Colonic Neoplasms; Plasmacytoma; Pancreatic Neoplasms; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Myelodysplastic Syndromes; Neurofibromatosis 2; Neoplasms; Blister; Fibrosis; Sepsis; Carcinoma, Verrucous; Details
Ranibizumab RG-3645; rhu-Fab-VEG; AMD-rhuFab-V2; AMD-Fab; rhuFab-V2; RFB-002; Y-0317; RG-6321 Approved Novartis Pharma Ag, Genentech Inc Lucentis, 诺适得, Susvimo Japan Diabetic macular oedema Novartis Pharma Ag 2006-06-30 Vitreous Hemorrhage; Retinoblastoma; Wet Macular Degeneration; Vascular Diseases; Glaucoma; Diabetes Complications; Pseudoxanthoma Elasticum; Retinal Detachment; Retinal Neovascularization; Cardiovascular Diseases; Eye Diseases; Uveitis; Ischemia; Hemangioma; Choroidal Neovascularization; Macular Degeneration; Melanoma; Conjunctival Neoplasms; Retinopathy of Prematurity; Retinal Vein Occlusion; Diabetic Retinopathy; Port-Wine Stain; Corneal Neovascularization; von Hippel-Lindau Disease; Diabetes Mellitus; Myopia; Telangiectasis; Epistaxis; Cataract; Telangiectasia, Hereditary Hemorrhagic; Pterygium; Retinal Telangiectasis; Diabetic Angiopathies; Vitreous Detachment; Iris Diseases; Macular Edema; Vision Disorders; Glaucoma, Neovascular; Choroid Diseases; Optic Neuropathy, Ischemic; Strongyloidiasis; Depression; Neovascularization, Pathologic; Central Serous Chorioretinopathy; Histoplasmosis; Myopia, Degenerative; Retinal Diseases; Angioid Streaks; Pathologic Processes; Glaucoma, Open-Angle; Diabetic macular oe Details
Ranibizumab biosimilar (Xbrane) Approved Xbrane Biopharma Ab EU Wet Macular Degeneration; Diabetes Complications; Diabetic Retinopathy; Macular Edema Stada Arzneimittel Ag 2022-11-09 Macular Edema; Wet Macular Degeneration; Diabetes Complications; Macular Degeneration; Diabetic Retinopathy Details
Faricimab RG-7716; RO-6867461 Approved F. Hoffmann-La Roche Ltd, Genentech Inc Vabysmo EU Wet Macular Degeneration; Diabetes Complications; Macular Edema Roche Registration Gmbh 2022-01-28 Macular Edema; Choroid Diseases; Diabetic macular oedema; Wet Macular Degeneration; Diabetes Complications; Diabetic Retinopathy; Diabetes Mellitus; Retinal Vein Occlusion; Macular Degeneration; Choroidal Neovascularization Details
Bevacizumab biosimilar (mAbixience) MB02; BEVZ-92; BEVZ92-MB02; AP-01 Approved Mabxience Sa Alymsys United States Colorectal Neoplasms Amneal Pharmaceuticals Llc 2013-10-25 Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Betta/Mabworks) MIL-60 Approved Institute Of Basic Medicine, Chinese Academy Of Medical Sciences, Beijing Mabworks Biotech Co Ltd 贝安汀 Mainland China Glioblastoma; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Ovarian Epithelial Betta Pharmaceuticals Co Ltd 2021-11-24 Glioblastoma; Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular Details
Bevacizumab biosimilar (Bio-Thera Solutions) BAT-1706 Approved Bio-Thera Solutions Ltd 普贝希 Mainland China Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Glioblastoma; Peritoneal Neoplasms; Uterine Cervical Neoplasms Bio-Thera Solutions Ltd 2021-11-17 Ovarian Neoplasms; Carcinoma, Renal Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular Details
Bevacizumab biosimilar (Boan Biopharma) LY-01008 Approved Shandong Boan Biotechnology Co Ltd 博优诺 Mainland China Uterine Cervical Neoplasms; Carcinoma, Ovarian Epithelial Shandong Boan Biotechnology Co Ltd 2021-05-07 Glioblastoma; Carcinoma, Ovarian Epithelial; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Uterine Cervical Neoplasms Details
Bevacizumab biosimilar (Shanghai Henlius Biotech) HLX-04; HLX04-O Approved Shanghai Henlius Biotech Co Ltd 汉贝泰 Mainland China Glioblastoma; Carcinoma, Hepatocellular Shanghai Henlius Biotech Co Ltd 2021-11-30 Solid tumours; Carcinoma; Rectal Neoplasms; Glioblastoma; Carcinoma, Ovarian Epithelial; Wet Macular Degeneration; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Macular Degeneration; Carcinoma, Hepatocellular Details
Bevacizumab biosimilar (TOT Biopharm) TAB-008; TOT-102; TAB008; TOT102 Approved Tot Biopharm Co Ltd 朴欣汀, Pusintin Mainland China Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Glioblastoma; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms Tot Biopharm Co Ltd 2021-12-01 Carcinoma, Ovarian Epithelial; Glioblastoma; Peritoneal Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Ranibizumab biosimilar (Formycon/Bioeq) FYB-201 Approved Formycon, Bioeq Gmbh CIMERLI, Ranivisio EU Macular Edema; Choroidal Neovascularization; Diabetic Retinopathy; Wet Macular Degeneration; Diabetes Complications Midas Pharma Gmbh 2022-08-02 Macular Edema; Wet Macular Degeneration; Diabetic macular oedema; Diabetes Complications; Choroidal Neovascularization; Macular Degeneration; Retinal Vein Occlusion; Diabetic Retinopathy Details
Bevacizumab biosimilar (Samsung Bioepis) SP-8; SB-8 Approved Samsung Bioepis Co Ltd Aybintio EU Uterine Cervical Neoplasms; Carcinoma, Renal Cell; Fallopian Tube Neoplasms; Carcinoma, Ovarian Epithelial; Peritoneal Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Samsung Bioepis Nl Bv 2020-08-19 Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Breast Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Fallopian Tube Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Ranibizumab biosimilar (Samsung Bioepis) SB-11 Approved Samsung Bioepis Co Ltd BYOOVIZ United States Macular Degeneration; Macular Edema; Choroidal Neovascularization Samsung Bioepis Co Ltd 2021-08-18 Macular Edema; Wet Macular Degeneration; Diabetic macular oedema; Macular Degeneration; Diabetic Retinopathy; Choroidal Neovascularization; Retinal Vein Occlusion Details
Bevacizumab biosimilar (Innovent Biologics) IBI-305; IBI305; IBI 305; CHS-305 Approved Innovent Biologics(Suzhou) Co Ltd 达攸同, BYVASDA, Bevagen Indonesia Triple Negative Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Ovarian Neoplasms; Uterine Cervical Neoplasms; Colorectal Neoplasms Innovent Biologics(Suzhou) Co Ltd 2020-06-17 Ovarian Neoplasms; Carcinoma, Ovarian Epithelial; Glioblastoma; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Ranibizumab biosimilar (CJSC Generium) GNR-067 Phase 1 Clinical Cjsc Generium Macular Degeneration Details
Colorectal cancer vaccine (Immunovo/Pepscan Therapeutics) Phase 1 Clinical Pepscan Systems Colorectal Neoplasms Details
Ranibizumab biosimilar (Reliance Life Sciences Group) R-TPR-024 Phase 3 Clinical Reliance Life Sciences Macular Degeneration Details
SCT-501(National Cancer Institute) SCT-501 Phase 2 Clinical National Cancer Institute Kidney Neoplasms Details
Ziv-aflibercept biosimiliar (Boan Biopharma) LY-01012; BA-1103 Phase 1 Clinical Shandong Boan Biotechnology Co Ltd Colorectal Neoplasms Details
Bevacizumab biosimilar (Gedeon Richter) Phase 1 Clinical Gedeon Richter Plc Neoplasms Details
Aflibercept biosimilar (Amgen) ABP-938 Phase 2 Clinical Amgen Inc Macular Degeneration Details
Bevacizumab biosimilar(Guangdong Dongyangguang) Phase 1 Clinical Guangdong Dongyangguang Pharmaceutical Co Ltd Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Shanghai Kangdai) Phase 1 Clinical Shanghai Kanda Bio-Technology Co Ltd Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Tanvex BioPharma) TX-16 Phase 1 Clinical Tanvex Biopharma Colorectal Neoplasms Details
Bevacizumab biosimilar(Guilin Sanjin) Phase 1 Clinical Guilin Sanjin Pharmaceutical Co Ltd Macular Degeneration Details
Bevacizumab biosimilar(Bioxpress) BXT-2316 Clinical Bioxpress Therapeutics Sa Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Glioblastoma; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
Aflibercept biosimilar (Zein Bioteccnology) Phase 1 Clinical Zein Bioteccnology Co Ltd Diabetic macular oedema Details
CLS-1002 CLS-1002 Phase 1 Clinical Clearside Biomedical Inc Macular Degeneration Details
Ranibizumab biosimilar (Pfenex) PF-582 Pfenex Details
Aflibercept biosimilar (Sam Chun Dang Pharm) SCD-411 Sam Chun Dang Pharm Co Ltd Details
FYB-203 FYB-203 Formycon Details
Aflibercept biosimilar (Mabwell) 9-MW-0813; 9MW-0813; 9MW0813; 9-MW0813 Phase 3 Clinical Mabwell (Shanghai) Bioscience Co Ltd Diabetic macular oedema Details
DE-120 DE-120 Santen Details
AG-13958 AG-13958; AG-013958 Pfizer Inc Details
Ranibizumab biosimilar (Qilu Pharmaceutical) BCD-300; QL-1205 Phase 3 Clinical Qilu Pharmaceutical Co Ltd, Biocnd Wet Macular Degeneration; Macular Degeneration Details
Ranibizumab biosimilar (Chong Kun Dang Pharmaceutical) CKD-701 Chong Kun Dang Pharmaceutical Corp Details
SNN-0029 sNN-0029 Newron Pharmaceutical Details
Bevacizumab biosimilar (Boehringer Ingelheim) BI-695502 C.H. Boehringer Sohn Ag & Co. Kg Details
Ranibizumab biosimilar (Lupin) LUBT-010 Phase 3 Clinical Rubin Ltd Macular Degeneration Details
Bevacizumab biosimilar (North China Pharmaceutical) MG-021 Phase 1 Clinical North China Pharmaceutical Company Ltd Colorectal Neoplasms; Macular Degeneration; Carcinoma, Non-Small-Cell Lung Details
Dilpacimab ABT-165; DVD-Ig ABT-165 Phase 1 Clinical Abbvie Inc Solid tumours; Neoplasms Details
ALS-L1023 ALS-L1023 Phase 2 Clinical Angiolab Inc Non-alcoholic Fatty Liver Disease; Metabolic Syndrome; Macular Degeneration Details
OB-318 OB-318 Phase 1 Clinical Oneness Biotech Co Ltd Solid tumours; Carcinoma, Hepatocellular Details
Bevacizumab biosimilar(Zhejiang Teruisi Pharmaceutical) TRS-003 Phase 3 Clinical Zhejiang Teruisi Pharmaceutical Inc Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Varisacumab R-84; GNR-011; AT-001-IBCG Phase 3 Clinical Peregrine, The University Of Texas Southwestern Medical Center Glioblastoma; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
IBI-324 IBI-324 Phase 1 Clinical Innovent Biologics (Usa), Inc Diabetic macular oedema Details
Ranibizumab biosimilar (Shanghai United Cell Biotechnology) Phase 1 Clinical Shanghai United Cell Biotechnology Co Ltd Macular Edema; Macular Degeneration Details
MP-0250 MP-0250 Phase 2 Clinical Molecular Partners Ag Neoplasms; Multiple Myeloma; Carcinoma, Non-Small-Cell Lung Details
CT-P42 CT-P42 Phase 3 Clinical Celltrion Inc Diabetic macular oedema Details
Aflibercept Biosimilar (Alteogen) ALT-L9 Phase 3 Clinical Alteogen Inc, Kissei Pharmaceutical Co Ltd Macular Degeneration Details
Bevacizumab biosimilar (Genor Biopharma) GB-222 Phase 3 Clinical Genor Biopharma Co Ltd Brain Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Alphamab/R-Pharm) RPH-001 Phase 3 Clinical R-Pharm Colorectal Neoplasms Details
Bevacizumab biosimilar (Beijing Science Sun/Beijing Lvzhu) K-11 Phase 3 Clinical Beijing Lvzhu Biological Technology Co Ltd, Beijing Science Sun Pharmaceutical Co Ltd Liver Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular Details
Bevacizumab biosimilar (Centus Biotherapeutics) FKB-238 Phase 3 Clinical Fujifilm Kyowa Kirin Biologics Co Ltd Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Breast Neoplasms; Peritoneal Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms Details
ASKG-712 AM-712; ASKG-712 Phase 1 Clinical Wet Macular Degeneration; Macular Degeneration Details
Bevacizumab biosimilar(Laboratorios Sophia) PRO-169 Phase 3 Clinical Laboratorios Sophia Sa De Cv Diabetic macular oedema Details
Aflibercept Biosimilar(Alvotech Swiss) AVT-06 Phase 3 Clinical Alvotech Swiss Ag Macular Degeneration Details
Sevacizumab SIM-BD-0801; EPI-0030; BD-0801; TK-001; APX-003; 9MW0211; 9MW-0211; MW02; MW-02 Phase 3 Clinical Epitomics Inc, Apexigen Inc Ovarian Neoplasms; Solid tumours; Carcinoma, Ovarian Epithelial; Wet Macular Degeneration; Colorectal Neoplasms; Peritoneal Neoplasms; Fallopian Tube Neoplasms; Macular Degeneration Details
VEGFA-targeting Gene Therapy(BDgene) BD311 Phase 1 Clinical Shanghai BDgene Technology Co Ltd Diabetic macular oedema; Macular Degeneration; Retinal Vein Occlusion Details
Muparfostat sodium PI-88 Phase 3 Clinical Australian National University Solid tumours; Liver Neoplasms; Neoplasms; Prostatic Neoplasms; Lung Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Melanoma Details
Emvododstat PTC-299 Phase 3 Clinical Ptc Therapeutics Inc Pneumonia; Neoplasms; Neurofibromatosis 2; Coronavirus Disease 2019 (COVID-19); Central Nervous System Neoplasms; Brain Neoplasms; Breast Neoplasms; Coronavirus Infections; Leukemia, Myeloid, Acute; Sarcoma, Kaposi Details
Vanucizumab RG-7221; RO-5520985; B800Z06O8K (UNII code) Phase 1 Clinical F. Hoffmann-La Roche Ltd Solid tumours; Neoplasms; Colorectal Neoplasms Details
Aflibercept biosimilar (CinnaGen) Phase 3 Clinical Cinnagen Macular Degeneration Details
Bevacizumab biosimilar (Eastern Biotech) JY-028 Phase 2 Clinical Beijing Eastern Biotech Co Ltd Wet Macular Degeneration; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Macular Degeneration Details
IBI-333 IBI-333 Phase 1 Clinical Innovent Biologics (Usa), Inc Wet Macular Degeneration; Macular Degeneration Details
Aflibercept biosimilar (Momenta/Mylan) M-710; MYL-1701P Phase 3 Clinical Mylan Nv, Momenta Diabetic macular oedema Details
TR-009 NOV-1501; ABL001-ABL Bio; ABL-001-ABL Bio; ES-104; CTX-009 Phase 3 Clinical Abl Bio Inc Biliary Tract Neoplasms; Solid tumours; Rectal Neoplasms; Colonic Neoplasms; Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Bile Duct Neoplasms; Gallbladder Neoplasms Details
BI-836880 BI-836880 Phase 2 Clinical Ablynx Nv Neoplasms; Wet Macular Degeneration Details
Bevacizumab biosimilar (Hualan Biological Engineering) WBP-264 Phase 3 Clinical Hualan Genetic Engineering Co Ltd Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
ELGN-EYE ELGN-EYE Phase 2 Clinical Elgan Pharma Ltd Retinopathy of Prematurity Details
Bevacizumab biosimilar (JHL Biotech) JHL-1149 Phase 1 Clinical JHL Biotech Neoplasms Details
Bevacizumab biosimilar(Shanghai Institute Of Biological Products) SIBP-04 Phase 1 Clinical Shanghai Institute Of Biological Products Co Ltd Details
Aflibercept Biosimilar (Boan Biopharma/Luye Pharma） LY-09004; BA-9101; OT-702 Phase 3 Clinical Shandong Boan Biotechnology Co Ltd, Luye Pharma Group Ltd Wet Macular Degeneration; Macular Degeneration Details
Aflibercept biosimilar (Samsung Bioepis) SB-15 Phase 3 Clinical Samsung Bioepis Co Ltd Macular Degeneration Details
Bevacizumab biosimilar (Prestige BioPharma/Hanwha Biologics) HD-204 Phase 3 Clinical Hanwha Biologics Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Huaota Biopharm) JS-501; HOT-1010 Phase 3 Clinical Shanghai Huaota Biopharmaceutical Co Ltd, Shanghai Junshi Biosciences Co Ltd Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar (Fudan-Zhangjiang) Phase 3 Clinical Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd Colorectal Neoplasms; Macular Degeneration; Carcinoma, Non-Small-Cell Lung Details
Bevacizumab biosimilar(Jiangsu Aosaikang) ASK-1202; AMD-B; AK-3008; ASK-B1202; ASKB1202 Phase 3 Clinical Jiangsu Aosaikang Pharmaceutical Co Ltd Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details

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