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Your Position: ホーム > Her2

Her2

概要

Name:Receptor protein-tyrosine kinase erbB-2
Target Synonym:EC 2.7.10.1,HER-2/Neu,Herstatin,HER-2,TKR1,Receptor, ErbB-2,V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog,V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2,Neuroblastoma/Glioblastoma Derived Oncogene Homolog,C-Erb B2/Neu Protein,CD340 Antigen,EC:2.7.10.1,EC 2.7.10,MLN 19,CD340,Tyrosine kinase-type cell surface receptor HER2,Receptor tyrosine-protein kinase erbB-2,ERBB2,MLN19,Proto-oncogene Neu,Erb-B2 Receptor Tyrosine Kinase 2,V-E
Number of Launched Drugs:34
Number of Drugs in Clinical Trials:202
Lastest Research Phase:Approved

ライセンス

Project Name Modality Therapeutic Area Indications Stage Right Available
Anti-Her2 II / Anti-Her2 IV Bi-specific antibody ADC Bioconjugates Oncology/Cancer Solid tumor Preclinical Global
Her2xCD3 BsAb Bispecific antibody Oncology/Cancer HER2-positive Cancer Phase I Global

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製造番号 種類 製品説明 構造 純度 特徴
HE2-M82F3 Mouse Biotinylated Mouse Her2 / ErbB2 Protein, Fc,Avitag™ (MALS verified)
HE2-M82F3-structure
HE2-M82F3-sds
CHEK-ATP150 Human HEK293/Human ErbB2 Stable Cell Line
HE2-M82E3 Mouse Biotinylated Mouse Her2 / ErbB2 Protein, His,Avitag™ (MALS verified)
HE2-M82E3-structure
HE2-M82E3-sds
HE2-M5253 Mouse Mouse Her2 / ErbB2 Protein, Fc Tag (MALS verified)
HE2-M5253-structure
HE2-M5253-sds
HE2-C5253 Cynomolgus Cynomolgus Her2 / ErbB2 Protein, Fc Tag
HE2-C5253-structure
HE2-C5253-sds
HE2-C82F3 Cynomolgus Biotinylated Cynomolgus Her2 / ErbB2 Protein, Fc,Avitag™
HE2-C82F3-structure
HE2-C82F3-sds
MBS-C006 Human ActiveMax® Human Her2 μBeads, premium grade (for cells)
HE2-HA2H9 Human APC-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HP2H8 Human PE-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HA2H3 Human Alexa Fluor™ 488-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HA2H4 Human Alexa Fluor™ 555-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HA2H5 Human Alexa Fluor™ 647-Labeled Human Her2 / ErbB2 Protein, His TagStar Staining
HE2-HA2H7 Human APC-Labeled Human Her2 / ErbB2 Protein, His Tag (Site-specific conjugation)
HE2-HA2H7-structure
HE2-R52H8 Rabbit Rabbit Her2 / ErbB2 Protein, His Tag (MALS verified)
HE2-R52H8-structure
HE2-R52H8-sds
HE2-HF256 Human FITC-Labeled Human Her2 / ErbB2 Protein, Fc Tag
HE2-HF256-structure
HE2-HF256-sds
HE2-HP2E3 Human PE-Labeled Human Her2 / ErbB2 Protein, His Tag (Site-specific conjugation)
HE2-HP2E3-structure
HE2-H52H9 Human Human Her2 / ErbB2 (23-510) Protein, His Tag (MALS verified)
HE2-H52H9-structure
HE2-H52H9-sds
HE2-H52H3 Human Human Her2 / ErbB2 (S310Y) Protein, His Tag (MALS verified)
HE2-H52H3-structure
HE2-H52H3-sds
HE2-H52H2 Human Human Her2 / ErbB2 (S310F) Protein, His Tag
HE2-H52H2-structure
HE2-H52H2-sds
MBS-K006 Human Human HER2-coupled Magnetic Beads
HE2-H52H4 Human Human Her2 / ErbB2 (498-648) Protein, His Tag
HE2-H52H4-structure
HE2-H52H4-sds
HE2-HF224 Human FITC-Labeled Human Her2 / ErbB2 Protein, His Tag
HE2-HF224-structure
HE2-HF224-sds
HE2-H5255 Human Human Her2 / ErbB2 Protein, Mouse IgG2a Fc Tag (MALS verified)
HE2-H5255-structure
HE2-H5255-sds
HE2-C82E3 Cynomolgus Biotinylated Cynomolgus Her2 / ErbB2 Protein, His,Avitag™ (MALS verified)
HE2-C82E3-structure
HE2-C82E3-sds
HE2-H5212 Human Human Her2 / ErbB2 Protein, Tag Free (MALS verified)
HE2-H5212-structure
HE2-H5212-sds
HE2-C52Hb Cynomolgus Cynomolgus Her2 / ErbB2 Protein, His Tag (MALS verified)
HE2-C52Hb-structure
HE2-C52Hb-sds
EHM-V1 Mouse ELISA Assay Kit for Anti-HER-2 h-mAb in Mouse Serum
HE2-H82E2 Human Biotinylated Human Her2 / ErbB2 Protein, His,Avitag™, premium grade
HE2-H82E2-structure
HE2-H82E2-sds
HE2-H822R Human Biotinylated Human Her2 / ErbB2 Protein, His Tag, ultra sensitivity (primary amine labeling, long spacer) (MALS verified)
HE2-H822R-structure
HE2-H822R-sds
HE2-H5287 Human Human Her2 / ErbB2 Protein, Twin-Strep Tag
HE2-H5287-structure
HE2-H5287-sds
ER2-M5220 Mouse Mouse Her2 / ErbB2 Protein, His Tag (MALS verified)
ER2-M5220-structure
ER2-M5220-sds
HE2-H5253 Human Human Her2 / ErbB2 Protein, Fc Tag, premium grade
HE2-H5253-structure
HE2-H5253-sds
HE2-H5225 Human Human Her2 / ErbB2 Protein, His Tag (MALS verified)
HE2-H5225-structure
HE2-H5225-sds
ACRO Quality

生物活性データの一部

HE2-HA2H9-Cell-based assay
Her2 CAR_T

5e5 of anti-Her2 CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer) of APC-Labeled Human Her2, His Tag (Cat. No. HE2-HA2H9) and negative control protein respectively (Fig. C and B), and non-transfected 293 cells were used as a control (Fig. A). APC signal was used to evaluate the binding activity (QC tested).

Protocol
HE2-H82E2-SPR
Her2 SPR

Herceptin captured on Protein A Chip can bind Biotinylated Human Her2, His, Avitag, premium grade (Cat. No. HE2-H82E2) with an affinity constant of 30.9 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol
HE2-H5225-SPR
Her2 SPR

Herceptin (Trastuzumab) captured on CM5 chip via anti-human IgG Fc antibodies surface, can bind Human Her2, His Tag (Cat. No. HE2-H5225) with an affinity constant of 1.07 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Protocol

カスタマーレビュー

Synonym Name

ERBB2,CD340,HER-2/neu,HER2,MLN19,NEU,NGL,TKR1

Background

Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2,HER-2 /neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation .

Clinical and Translational Updates

公開薬物情報

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Trastuzumab biosimilar (AryoGen Pharmed) Approved Aryogen Biopharma AryoTrust Stomach Neoplasms; Breast Neoplasms Details
Trastuzumab/Hyaluronidase Approved Genentech Inc Herceptin Hylecta United States Breast Neoplasms Genentech Inc 2019-02-28 Breast Neoplasms Details
Trastuzumab biosimilar (Dr. Reddy's Laboratories) Approved Dr Reddy's Laboratories Ltd Hervycta India Breast Neoplasms Dr Reddy's Laboratories Ltd 2018-07-26 Breast Neoplasms Details
Trastuzumab biosimilar (Intas Pharmaceuticals) Approved Intas Biopharmaceuticals Breast Neoplasms Details
Trastuzumab biosimilar (AXXO) Approved Axxo Breast Neoplasms Details
Trastuzumab biosimilar (Reliance Life Sciences) R-TPR-016 Approved Reliance Life Sciences TrastuRel India Breast Neoplasms Reliance Life Sciences 2015-01-01 Breast Neoplasms Details
Trastuzumab biosimilar (Zydus) Approved Zydus Cadila Vivitra India Breast Neoplasms Zydus Cadila 2016-01-01 Breast Neoplasms Details
Trastuzumab biosimilar (Biocad) BCD-022 Approved Biocad HERtiCAD Russian Federation Breast Neoplasms Biocad 2016-01-01 Breast Neoplasms Details
Trastuzumab emtansine biosimilar (Zydus Cadila) ZRC-3256 Approved Zydus Cadila Ujvira India Breast Neoplasms Zydus Cadila 2021-05-24 Breast Neoplasms Details
Trastuzumab/Pertuzumab RO-7198574; RG-6264 Approved F. Hoffmann-La Roche Ltd Phesgo EU Breast Neoplasms Roche Registration Gmbh 2020-06-29 Breast Neoplasms; Metastatic breast cancer Details
Trastuzumab biosimilar (Shanghai Henlius Biotech) HLX-02 Approved Shanghai Henlius Biotech Co Ltd Zercepac, 汉曲优 Australia Stomach Neoplasms; Breast Neoplasms Cipla Australia Pty Ltd 2020-07-27 Stomach Neoplasms; Neoplasms; Breast Neoplasms Details
Ado-trastuzumab emtansine RG-3502; R-3502; T-DM1; PRO-132365; RO-5304020 Approved Genentech Inc Kadcyla, 赫赛莱 Mainland China Breast Neoplasms Roche Pharma (Schweiz) Ag 2013-02-22 Solid tumours; Hematologic Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Salivary Gland Neoplasms; Urinary Bladder Neoplasms; Multiple Myeloma; Breast Neoplasms; Cholangiocarcinoma; Urologic Neoplasms; Lung Neoplasms; Lymphoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung Details
Tucatinib ARRY-380; ONT-380; MK-7119 Approved Array Biopharma Tukysa EU Breast Neoplasms Seagen Netherlands Bv 2020-04-17 Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Breast Neoplasms; Hepatic Insufficiency; Meningeal Neoplasms; Colorectal Neoplasms; Metastatic breast cancer; Neoplasm Metastasis Details
Disitamab Vedotin RC-48-ADC; RC48-ADC; RC-48 Approved RemeGen Co Ltd 爱地希 Mainland China Carcinoma, Transitional Cell RemeGen Co Ltd 2021-06-08 Liver Neoplasms; Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Genital Diseases, Female; Esophageal Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Bile Duct Neoplasms; Genital Neoplasms, Female; Breast Diseases; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Melanoma Details
Dacomitinib PF-299; PF-804; PF-299804; PF-00299804; PF-00299804-3; PF-00299804-03 Approved Pfizer Inc Vizimpro Mainland China Carcinoma, Non-Small-Cell Lung Pfizer Europe Ma Eeig 2018-09-27 Colorectal Neoplasms; Adenocarcinoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Penile Neoplasms; Lung Neoplasms; Esophageal Squamous Cell Carcinoma; Mouth Neoplasms; Head and Neck Neoplasms; Brain Neoplasms; Carcinoma, Large Cell; Liver Diseases; Glioblastoma; Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Solid tumours Details
Pertuzumab RG-1273; RO-4368451-F01; rhuMab-2C4; RO-4368451; R-1273 Approved Genentech Inc Perjeta, Omnitarg Mainland China Breast Neoplasms Roche Pharma (Schweiz) Ag 2012-06-08 Neuroendocrine Tumors; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Fallopian Tube Neoplasms; Multiple Endocrine Neoplasia; Carcinoma, Neuroendocrine; Peritoneal Neoplasms; Neuroblastoma; Prostatic Neoplasms; Breast Neoplasms; Adrenal Gland Neoplasms; Ovarian Neoplasms; Neoplasms; Pancreatic Neoplasms; Colonic Neoplasms; Pancreatic neuroendocrine tumors (pNET); Rectal Neoplasms; Carcinoid Tumor; Stomach Neoplasms; Esophageal Neoplasms; Solid tumours Details
Trastuzumab biosimilar (Biocon/Mylan) Bmab-200; Myl-1401O; HerMyl-1401O Approved Biocon Ltd, Mylan Nv CANMAb, Ogivri, Zedora, Hertraz EU Breast Neoplasms; Stomach Neoplasms Viatris Ltd 2013-01-01 Esophageal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Esophageal adenocarcinoma; Adenocarcinoma; Uterine Cervical Neoplasms Details
Trastuzumab biosimilar (Pfizer) PF-5280014; PF-05280014 Approved Pfizer Inc Trazimera Japan Breast Neoplasms; Stomach Neoplasms Pfizer Inc 2018-07-26 Urinary Bladder Neoplasms; Melanoma; Uterine Cervical Neoplasms; Thyroid Neoplasms; Esophageal adenocarcinoma; Endometrial Neoplasms; Uterine Neoplasms; Lung Neoplasms; Glioma; Lymphoma; Colorectal Neoplasms; Cholangiocarcinoma; Prostatic Neoplasms; Breast Neoplasms; Liver Neoplasms; Multiple Myeloma; Carcinoma, Ovarian Epithelial; Skin Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Colonic Neoplasms; Esophageal Neoplasms; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Rectal Neoplasms; Stomach Neoplasms; Solid tumours; Ovarian Neoplasms Details
Afatinib Dimaleate BIBW-2992; BIBW-2992-MA2 Approved C.H. Boehringer Sohn Ag & Co. Kg Gilotrif, Tomtovok, 吉泰瑞, Tovok, Giotrif Mainland China Carcinoma, Non-Small-Cell Lung Boehringer Ingelheim International Gmbh 2013-07-12 Lymphoma; Prostatic Neoplasms; Brain Neoplasms; Urethral Neoplasms; Colorectal Neoplasms; Urologic Neoplasms; Ureteral Neoplasms; Carcinoma, Squamous Cell; Lung Neoplasms; Breast Neoplasms; Uterine Neoplasms; Glioma; Esophageal Squamous Cell Carcinoma; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Hematologic Neoplasms; Liver Diseases; Urinary Bladder Neoplasms; Chordoma; Multiple Myeloma; Neuroectodermal Tumors; Glioblastoma; Neoplasms; Neoplasms, Squamous Cell; Renal Insufficiency; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Stomach Neoplasms; Rhabdomyosarcoma; Head and Neck Neoplasms; Solid tumours Details
Fam-trastuzumab deruxtecan DS-8201a; DS-8201 Approved Daiichi Sankyo Co Ltd Enhertu United States Carcinoma, Non-Small-Cell Lung Daiichi Sankyo Co Ltd 2019-12-20 Osteosarcoma; Uterine Cervical Neoplasms; Neoplasm Metastasis; Gastrointestinal Neoplasms; Adenocarcinoma; Carcinoma, Endometrioid; Carcinoma, Non-Small-Cell Lung; Brain metastases; Metastatic breast cancer; Meningeal Neoplasms; Colorectal Neoplasms; Ovarian Neoplasms; Breast Neoplasms; Urinary Bladder Neoplasms; Neoplasms; Neoplasms, Glandular and Epithelial; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Solid tumours; Biliary Tract Neoplasms Details
Trastuzumab R-597; RO45-2317; Anti-HER2/neu-MAb; huMAb4D5-8; RG-597; MKC-454 Approved Genentech Inc Herceptin, 赫赛汀 Mainland China Stomach Neoplasms Roche Pharma (Schweiz) Ag 1998-09-25 Sarcoma; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Adenocarcinoma; Lung Neoplasms; Metastatic breast cancer; Vulvar Diseases; Endometrial Neoplasms; Urologic Neoplasms; Carcinoma, Mucoepidermoid; Carcinoma, Acinar Cell; Urethral Neoplasms; Prostatic Neoplasms; Solid tumours; Breast Neoplasms; Urinary Bladder Neoplasms; Salivary Gland Neoplasms; Colonic Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Stomach Neoplasms; Meningeal Carcinomatosis; Esophageal Neoplasms; Head and Neck Neoplasms; Neoplastic Cells, Circulating; Ependymoma Details
Lapatinib Ditosylate Hydrate GW-572016; GW-572016F; GW-2016 Approved Glaxosmithkline Plc, Novartis Pharma Ag Tykerb, Tyverb, 泰立沙, Tykerb/Tyverb Mainland China Breast Neoplasms Glaxosmithkline Ag 2007-03-13 Neoplasms, Gonadal Tissue; Carcinoma, Acinar Cell; Carcinoma, Mucoepidermoid; Colorectal Neoplasms; Astrocytoma; Gliosarcoma; Bile Duct Neoplasms; Carcinoma, Squamous Cell; Lymphoma; Glioma; Brain metastases; Lung Neoplasms; Endometrial Neoplasms; Brain Neoplasms; Laryngeal Neoplasms; Gallbladder Neoplasms; Adenocarcinoma; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Neoplasm Metastasis; Tongue Neoplasms; Melanoma; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Neuroma, Acoustic; Pancreatic Neoplasms; Ovarian Neoplasms; Head and Neck Neoplasms; Ependymoma; Liver Neoplasms; Medulloblastoma; Stomach Neoplasms; Esophageal Neoplasms; Abdominal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Carcinoma; Carcinoma, Ovarian Epithelial; Solid tumours; Carcinoma, Verrucous; Glioblastoma; Salivary Gland Neoplasms; Neoplasms; Neurofibromatosis 2; Urinary Bladder Neoplasms; Carcinoma, Adenoid Cystic; Central Nervous System Neoplasms; Oligodendroglioma; Breast Neoplasms; Prost Details
Osimertinib Mesylate AZD-9291; RDL94R2A16; AZD-9291 Mesylate; AZD9291 Approved Astrazeneca Pharmaceutical Co Ltd 泰瑞沙, Tagrisso Mainland China Carcinoma, Non-Small-Cell Lung Astrazeneca Ab 2015-11-13 Uterine Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Meningeal Neoplasms; Colorectal Neoplasms; Carcinoma, Squamous Cell; Lung Neoplasms; Brain metastases; Esophageal adenocarcinoma; Cholangiocarcinoma; Lymphoma; Glioma; Endometrial Neoplasms; Thyroid Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Melanoma; Adenocarcinoma of Lung; Liver Neoplasms; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Rectal Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Solid tumours; Carcinoma, Ovarian Epithelial; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Skin Neoplasms; Colonic Neoplasms; Glioblastoma; Multiple Myeloma; Urinary Bladder Neoplasms Details
Pyrotinib Maleate HTI-1001; SHR-1258; BLTN Approved Jiangsu Hengrui Medicine Co Ltd 艾瑞妮 Mainland China Breast Neoplasms Jiangsu Hengrui Medicine Co Ltd 2018-08-12 Solid tumours; Biliary Tract Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Adenocarcinoma of Lung; Neoplasms; Breast Neoplasms; Bile Duct Neoplasms; Metastatic breast cancer; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms Details
Neratinib Maleate CAN-030; HKI-272; PF-0528767; WAY-179272; PB-272 Approved Pfizer Pharmaceuticals Ltd (China) Nerlynx, 贺俪安 Mainland China Breast Neoplasms Excella Gmbh & Co Kg 2017-07-17 Solid tumours; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Prostatic Neoplasms; Hepatic Insufficiency; Colorectal Neoplasms; Lung Neoplasms; Metastatic breast cancer; Brain metastases; Carcinoma, Non-Small-Cell Lung Details
Inetetamab CMAB-302 Approved Shanghai Cp Guojian Pharmaceutical Co Ltd Cipterbin, 赛普汀 Mainland China Breast Neoplasms Shanghai Cp Guojian Pharmaceutical Co Ltd 2020-06-17 Breast Neoplasms Details
Margetuximab MGAH-22 Approved Macrogenics Inc Margenza United States Breast Neoplasms Macrogenics Inc 2020-12-16 Ovarian Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Trastuzumab biosimilar (Samsung Bioepis) SB-3; AMT-901 Approved Samsung Bioepis Co Ltd Samfenet, Ontruzant United States Breast Neoplasms; Stomach Neoplasms Samsung Bioepis Co Ltd 2017-11-15 Stomach Neoplasms; Breast Neoplasms Details
Trastuzumab biosimilar (Synthon) ABP-980 Approved Synthon Bv Kanjinti United States Breast Neoplasms; Stomach Neoplasms Amgen Inc 2018-05-16 Breast Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Melanoma; Endometrial Neoplasms; Esophageal adenocarcinoma; Uterine Neoplasms; Lung Neoplasms; Thyroid Neoplasms; Glioma; Lymphoma; Colorectal Neoplasms; Prostatic Neoplasms; Cholangiocarcinoma; Carcinoma, Intraductal, Noninfiltrating; Ovarian Neoplasms; Urinary Bladder Neoplasms; Multiple Myeloma; Carcinoma, Ovarian Epithelial; Skin Neoplasms; Carcinoma, Transitional Cell; Pancreatic Neoplasms; Colonic Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Stomach Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Solid tumours; Liver Neoplasms Details
Trastuzumab biosimilar (Celltrion) CT-P6; CT-P06 Approved Celltrion Inc Herzuma United States Breast Neoplasms Celltrion Inc 2014-01-01 Stomach Neoplasms; Breast Neoplasms Details

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Recombinant anti-HER2 humanized monoclonal antibody (Shenzhen Main Luck Pharmaceuticals) Phase 1 Clinical Shenzhen Main Luck Pharmaceuticals Inc Breast Neoplasms Details
Pertuzumab biosimilar (CTTQ) TQB-2440 Phase 3 Clinical Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Breast Neoplasms Details
Recombinant humanized anti-HER2 antibody (Hisun Pharma) Phase 3 Clinical Zhejiang Hisun Pharmaceutical Co Ltd Breast Neoplasms Details
JRF-103 JRF103; JRF-103 Phase 2 Clinical Shenzhen Jinrui Foundation Biotechnology Co Ltd Solid tumours Details
Trastuzumab biosimilar(Aprogen/Nichi-Iko) AP-06 Phase 3 Clinical Nichi-Iko Pharmaceutical Co Ltd, Aprogen Breast Neoplasms Details
Anti-HER2 CAR T-cell therapy (Baylor College of Medicine/The Hospital for Sick Children/Texas Children's Hospital/The Methodist Hospital System ) Phase 1 Clinical Baylor College Of Medicine, The Hospital For Sick Children, Texas Children'S Hospital, The Methodist Hosp Research Institute Sarcoma Details
SSGJ-706 SSGJ-706 Phase 1 Clinical Shanghai Cp Guojian Pharmaceutical Co Ltd Solid tumours; Lymphoma Details
PM-3002 PM-3002 Phase 1 Clinical Biotheus Inc Details
99mTc- ADAPT6 99mTc- ADAPT6; ADAPT6; SNA-018 Phase 1 Clinical Uppsala University, Kth Royal Institute Of Technology Breast Neoplasms Details
BAY-2701439 BAY-2701439 Phase 1 Clinical Bayer AG Neoplasms Details
TAA-013 TAA-013 Phase 3 Clinical Tot Biopharm Co Ltd Breast Neoplasms Details
HL-02 HL-02 Phase 3 Clinical Hualan Genetic Engineering Co Ltd Breast Neoplasms Details
TGFBeta-resistant-HER2-EBV-CTLs TGFBeta-resistant-HER2-EBV-CTLs Phase 1 Clinical Baylor College Of Medicine Neoplasms Details
Trastuzumab biosimilar (United BioPharma) UB-921 Phase 1 Clinical United Biopharma Inc Breast Neoplasms Details
IBPM002BZ (Inbiopro Solutions) IBPM-002BZ Clinical Inbiopro Solutions Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Colorectal Neoplasms Details
Trastuzumab biosimilar (Hualan Biological Engineering) Phase 1 Clinical Hualan Genetic Engineering Co Ltd Stomach Neoplasms; Breast Neoplasms Details
IBPM003TZ (Inbiopro Solutions) IBPM-003TZ Clinical Inbiopro Solutions Breast Neoplasms Details
PB-357 PB-357 Phase 1 Clinical Pfizer Inc Neoplasms Details
Anti-HER2 CAR T-cell therapy (Seattle Children's Hospital) Phase 1 Clinical Seattle Children'S Research Institute Central Nervous System Neoplasms Details
KSP-QRH-E3-IRDye800 Phase 1 Clinical University Of Michigan Cholangiocarcinoma Details
Recombinant anti-HER2 human monoclonal antibody-DM1 (Hisun Pharm/Mabworks Biotech) HS-630; HS630 Phase 1 Clinical Zhejiang Hisun Pharmaceutical Co Ltd, Beijing Mabworks Biotech Co Ltd Breast Neoplasms Details
SHR-A1201 SHR-A1201 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Breast Neoplasms Details
Anti-CD3 and anti-HER2 BiTE-expressing T cell (MedImmune) Phase 2 Clinical University Of Michigan, Huazhong University Of Science And Technology, University Of Virginia Cancer Center, Medimmune Breast Neoplasms Details
AU-101 AU-101 Phase 2 Clinical Aurora Biopharma Glioblastoma; Osteosarcoma; Breast Neoplasms Details
68Ga-anti-HER2 nanobodies (Universite Libre de Bruxelles) Phase 1 Clinical Universite Libre De Bruxelles Breast Neoplasms Details
MX-402 MX-402 Phase 1 Clinical Medvax Technologies Stomach Neoplasms Details
Recombinant anti-HER2 subdomain II humanized monoclonal antibody(Livzon) LZM-005 Phase 1 Clinical Livzon Pharmaceutical Group Inc Breast Neoplasms Details
Trastuzumab biosimilar (BioXpress) BXT-2318; BX-2318 Clinical Bioxpress Therapeutics Sa Stomach Neoplasms; Metastatic breast cancer Details
99m-Tc labeled anti-HER2 single domain antibody (NanoMab) 99mTc-NM-02 Phase 1 Clinical Nanomab Technology Ltd Breast Neoplasms Details
Pertuzumab biosimilar (Xuanzhu/SL) KM-118; KM118; XZP-KM118 Phase 1 Clinical Beijing Sl Pharmaceutical Co Ltd Breast Neoplasms Details
SSGJ-612 SSGJ-612 Phase 1 Clinical Shanghai Cp Guojian Pharmaceutical Co Ltd Solid tumours Details
Pertuzumab biosimilar (CinnaGen) Phase 3 Clinical Cinnagen Breast Neoplasms Details
Sirotinib Maleate XZP-5491 Phase 1 Clinical Shandong Xuanzhu Pharmaceutical Technology Co Ltd Stomach Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell Lung Details
GB-251 GB-251; NBT-828; GB221-NBT828 ADC-1 Phase 1 Clinical Genor Biopharma Co Ltd, Newbio Therapeutics Inc Breast Neoplasms; Metastatic breast cancer Details
Puvitinib Phase 1 Clinical Suzhou Teligene Ltd Solid tumours Details
KY-1701 KY-1701 Phase 1 Clinical Jiangsu Kanion Pharmaceutical Co Ltd Breast Neoplasms Details
GB-235 GB-235 Phase 1 Clinical Genor Biopharma Co Ltd Breast Neoplasms Details
Pertuzumab biosimilar (Jushi Biopharmaceutical ) Phase 1 Clinical Jushi Biopharmaceutical Co Ltd Breast Neoplasms; Metastatic breast cancer Details
Epertinib S-222611 Phase 2 Clinical Shionogi & Co Ltd Neoplasms Details
AU-105 AU-105 Phase 2 Clinical Aurora Biopharma Glioblastoma Details
99mTc-DARPinG3 99mTc-DARPinG3; 99mTc-DARPinG-3 Clinical Tomsk National Research Medical Center Of The Russian Academy Of Sciences Breast Neoplasms Details
I-025-A I-025-A Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Breast Neoplasms Details
Trastuzumab biosimilar (Zhejiang Hisun Pharmaceutical) HS-022 Phase 1 Clinical Zhejiang Hisun Pharmaceutical Co Ltd Breast Neoplasms Details
HER2/neu cancer vaccine (University of Washington/Corixa/GSK) University Of Washington Details
CP-724714 CP-724714 Pfizer Pharmaceuticals Ltd (China) Details
Mubritinib TAK-165 Takeda Pharmaceutical Co Ltd Details
MBS-301 MBS-301 Phase 1 Clinical Beijing Mabworks Biotech Co Ltd Stomach Neoplasms; Breast Neoplasms Details
Dual-targeting HER2 and PD-L1 CAR-T Cell Therapy (Sichuan University) Sichuan University Details
MP-412 AV-412; MP-412 Mitsubishi Tanabe Pharma Details
BVAC-B vaccine (Cellid) BVAC-B Cellid Company Details
TAK-285 TAK-285 Takeda Details
BCD-147 BCD-147 Biocad Details
M-802(Wuhan Yzy Biopharma/CSPC Pharmaceutical) M-802 Phase 1 Clinical Wuhan Yzy Biopharma Co Ltd, CSPC Pharmaceutical Group Ltd Solid tumours; Ovarian Neoplasms; Stomach Neoplasms; Breast Neoplasms Details
Recombinant anti-HER2 humanized monoclonal antibody complex B-002 Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Breast Neoplasms Details
MP-0274 DARPin-41; SPA-28; CME-114; CME-115; CME-118; CME-119; MP-0274 Molecular Partners Ag Details
Anti-HER2 monoclonal antibody-MCC-DM1 conjugate (Shanghai Pharma) B-003 (Shanghai Pharma) Phase 1 Clinical Shanghai Crosslink Pharmaceutical R & D Co Ltd, Shanghai Pharmaceuticals Holding Co Ltd Breast Neoplasms Details
MEDI-4276 MEDI-4276 Medimmune Llc Details
RG-6148 RG-6148; DHES-0815A F. Hoffmann-La Roche Ltd Details
Hemay-022 Hemay-022 Phase 3 Clinical Tianjin Hemay Pharmaceutical Co Ltd, Xiajiang Hemei Pharmaceutical Co Ltd Breast Neoplasms; Foodborne Diseases Details
DZD-1516 DZD-1516 Phase 1 Clinical Dizal (Jiangsu) Pharmaceutical Co Ltd Breast Neoplasms Details
Recombinant anti-HER2 domain II humanized monoclonal antibody (Qilu Pharmaceutical) Phase 1 Clinical Qilu Pharmaceutical Co Ltd Breast Neoplasms Details
Recombinant human ErbB3 fragment vaccine (Zensun) rhErbB3-f Phase 1 Clinical Zensun (Shanghai) Sci&Tech Co Ltd Neoplasms Details
Recombinant Humanized Anti-Human Epidermal Growth Factor Receptor Monoclonal Antibody and the Dolastatins Derivative DUO5 Conjugated ZV0203; ZV203 Phase 1 Clinical Zhejiang Hisun Pharmaceutical Co Ltd, Zhejiang Zova Biotherapeutics Inc, Concortis Biosystems Corp Solid tumours Details
Selatinib Ditosilate QLNC-120 Phase 2 Clinical Qilu Antibiotics (Linyi) Pharmaceutical Co Ltd, Qilu Pharmaceutical Co Ltd Breast Neoplasms Details
Allitinib Tosylate AST-6; ALS-1306; AST-1306 Phase 2 Clinical Shanghai Allist Pharmaceutical Technology Co Ltd Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
AMX-3009 Maleate AMX-3009; AMX3009马来酸 Phase 1 Clinical Anrun Medicine Technology (Suzhou) Co Ltd Solid tumours; Stomach Neoplasms; Pancreatic Neoplasms; Breast Neoplasms Details
BAT-1006 BAT-1006 Phase 1 Clinical Bio-Thera Solutions Ltd Solid tumours Details
Pertuzumab biosimilar(EirGenix) EG-1206A; EG-1206-A Phase 1 Clinical Eirgenix Inc Breast Neoplasms Details
BC-004 BC-004 Phase 1 Clinical Shandong Buchang Pharmaceuticals Co Ltd Solid tumours; Breast Neoplasms Details
Recombinant anti-HER2 humanized monoclonal antibody (Shanghai Institute of Biological Products) SIBP-01 Phase 3 Clinical Shanghai Institute Of Biological Products Co Ltd Stomach Neoplasms; Breast Neoplasms Details
IMM-2902 IMM-2902 Phase 1 Clinical ImmuneOnco Biopharmaceuticals (Shanghai) Co Ltd Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
Recombinant anti-HER2 subdomain II and subdomain IV humanized monoclonal antibody(Xuanzhu) XZP-KM257; KM257/252; KM-257 Phase 1 Clinical Beijing Kangming Bio New Drug Development Co Ltd Solid tumours Details
Recombinant anti-HER2 humanized HuA21 monoclonal antibody(Hankemab) Phase 1 Clinical Solid tumours Details
NIP-142 NIP-142 Phase 1 Clinical Carcinoma, Non-Small-Cell Lung Details
trastuzumab biosimilar (Hetero) Ado-Trastuzumab biosimilar (Hetero) Phase 3 Clinical Hetero Drugs Ltd Neoplasms Details
Trastuzumab biosimilar (BioIntegrator) BI-Mab-03 Phase 1 Clinical Biointegrator Llc Breast Neoplasms Details
TT-16 TT-16 Phase 1 Clinical Tessa Therapeutics Ltd Solid tumours Details
Trastuzumab biosimilar (NeuClone/Serum Institute of India) Phase 1 Clinical Serum Institute Of India Ltd, Neuclone Stomach Neoplasms; Breast Neoplasms Details
MB-103 MB-103 Phase 1 Clinical Mustang Bio Inc, City Of Hope National Medical Center Glioblastoma; Brain metastases Details
HER2(EQ)BBzeta/CD19 T cells (City of Hope) Phase 1 Clinical Mustang Bio Inc, City Of Hope National Medical Center Glioma Details
SPH-5030 SPH-5030 Phase 1 Clinical Shanghai Pharmaceuticals Holding Co Ltd Solid tumours Details
ORIC-114 ORIC-114 Phase 1 Clinical Voronoi Solid tumours; Carcinoma, Non-Small-Cell Lung Details
HER2 cancer vaccine (BioLife Science) PEV-6; PEV-6A; IMU-131 Phase 2 Clinical Pevion Biotech Ltd Esophageal Neoplasms; Stomach Neoplasms; Gastrointestinal Neoplasms; Adenocarcinoma Details
MT-5111 MT-5111 Phase 1 Clinical Molecular Templates Inc Solid tumours Details
BDC-1001 BDC-1001 Phase 2 Clinical Bolt Biotherapeutics Inc Solid tumours Details
Iodine-131-SGMIB anti-HER2 monoclonal antibody [131I]-SGMIB Anti-HER2-VHH1; 131I-SGMIB-anti-HER2-VHH1; Iodine-131-SGMIB-anti-HER2-VHH1; CAM-H2 Phase 2 Clinical Camel-Ids Nv Stomach Neoplasms; Esophageal Neoplasms; Breast Neoplasms Details
TAC01-HER2 TAC01-HER2 Phase 2 Clinical Triumvira Immunologics Inc Solid tumours Details
NeuCeptin NeuCeptin Phase 1 Clinical Neuclone, Serum Institute Of India Ltd Stomach Neoplasms; Breast Neoplasms Details
Anti-CD3-anti-HER2-activated T cells Phase 2 Clinical Transtarget Breast Neoplasms; Prostatic Neoplasms Details
Pertuzumab biosimilar (Qilu Pharmaceutical) QL-1209 Phase 3 Clinical Qilu Pharmaceutical Co Ltd Breast Neoplasms Details
AE-37/GP-2 vaccine AE-37 (Generex Biotechnology Corporation) Phase 2 Clinical Generex Biotechnology Corp Triple Negative Breast Neoplasms; Breast Neoplasms Details
HER.CAR-CMV-specific-CTLs HER.CAR-CMV-specific-CTLs Phase 1 Clinical Baylor College Of Medicine Glioblastoma Details
4-1BBz CD19-Her2tG (Seattle Children's Hospital) Phase 1 Clinical Seattle Children'S Hospital Leukemia; Neoplasms; Lymphoma Details
Autologous-HER2-specific-T-cells Autologous-HER2-specific-T-cells Phase 1 Clinical Baylor College Of Medicine Sarcoma; Brain Neoplasms Details
Multiple 4SCAR-T Cell Therapy (Shenzhen Geno-Immune Medical Institute) Phase 2 Clinical Shenzhen Geno-Immune Medical Institute Breast Neoplasms Details
Autologous AdHER2 dendritic cell vaccine (National Cancer Institute) Phase 1 Clinical National Cancer Institute Neoplasms; Breast Neoplasms; Adenocarcinoma; Neoplasm Metastasis Details
ALT-P7 HM2-MMAE; ALT-P7 Phase 1 Clinical Alteogen Inc Stomach Neoplasms; Breast Neoplasms Details
Pertuzumab biosimilar（Hisun Pharm） HS-627; HS627 Phase 3 Clinical Zhejiang Hisun Pharmaceutical Co Ltd, Beijing Mabworks Biotech Co Ltd Breast Neoplasms Details
TPIV-100 (TapImmune) TPIV-100 Phase 2 Clinical Mayo Clinic Carcinoma, Intraductal, Noninfiltrating; Breast Neoplasms; Breast Neoplasms, Male Details
HER-2/Neu pulsed DC1 vaccine (University of Pennsylvania) Phase 1 Clinical University Of Pennsylvania, National Cancer Institute Breast Neoplasms Details
CIDeCAR Phase 1 Clinical Bellicum Pharmaceuticals Inc, National Cancer Institute Osteosarcoma; Sarcoma; Neuroblastoma; Melanoma Details
89Zr-ss-Pertuzumab Phase 1 Clinical Genentech Inc Breast Neoplasms; Metastatic breast cancer Details
HER-2 Specific CAR T Cell Phase 1 Clinical Pediatric Brain Tumor Consortium (Pbtc), St. Jude Children'S Research Hospital Ependymoma Details
HER2.taNK NK-92/5.28.z Phase 1 Clinical Nantkwest Inc Glioblastoma Details
Cinrebafusp alfa PRS-343 Phase 2 Clinical Pieris Pharmaceuticals Solid tumours; Stomach Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms Details
99mTc-HPArk2 99mTc-HPArk2; 99-mTc-HPArk-2 Phase 1 Clinical Peking Union Medical College Hospital Breast Neoplasms Details
Recombinant anti-HER2 antibody-Tub114 DAC-001; DX126-262 Phase 2 Clinical Hangzhou Dac Biotech Company Ltd Stomach Neoplasms; Carcinoma, Transitional Cell; Breast Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung Details
Pertuzumab biosimilar(Zydus Cadila) ZRC-3277 Phase 3 Clinical Zydus Cadila Breast Neoplasms Details
PLB-1004 PLB-1004 Phase 1 Clinical Beijing Anshi Biotechnology Co Ltd Carcinoma, Non-Small-Cell Lung Details
AB-201 (Artiva Biotherapeutics) Phase 1 Clinical Artiva Biotherapeutics Inc Solid tumours Details
ETBX-021 ETBX-021 Phase 2 Clinical Nantbioscience Inc, Etubics Corp Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Prostatic Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
CT-0508 Phase 1 Clinical Carisma Therapeutics Inc Digestive System Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Adenocarcinoma; Carcinoma, Squamous Cell; Carcinoma, Small Cell; Endometrial Neoplasms; Colorectal Neoplasms; Bile Duct Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms; Biliary Tract Neoplasms; Carcinoma, Ductal; Carcinoma, Transitional Cell; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Inflammatory Breast Neoplasms; Carcinoma, Ovarian Epithelial; Neoplasms; Stomach Neoplasms; Ovarian Neoplasms; Head and Neck Neoplasms; Solid tumours Details
SSGJ-705 SSGJ-705 Phase 1 Clinical Shanghai Cp Guojian Pharmaceutical Co Ltd Solid tumours; Neoplasms Details
MRG-002 MRG-002 Phase 2 Clinical Shanghai Miracogen Inc Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Carcinoma, Transitional Cell; Breast Neoplasms; Bile Duct Neoplasms; Metastatic breast cancer; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
A-166 A-166 Phase 2 Clinical Sichuan Kelun Pharmaceutical Co Ltd Mouth Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Prostatic Neoplasms; Carcinoma, Mucoepidermoid; Peritoneal Neoplasms; Bile Duct Neoplasms; Colorectal Neoplasms; Urologic Neoplasms; Urinary Bladder Neoplasms; Lip Neoplasms; Laryngeal Neoplasms; Tonsillar Neoplasms; Lung Neoplasms; Tongue Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Ovarian Neoplasms; Head and Neck Neoplasms; Solid tumours; Stomach Neoplasms; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Rectal Neoplasms; Cystadenocarcinoma, Mucinous; Liver Neoplasms; Pancreatic Neoplasms; Salivary Gland Neoplasms; Skin Neoplasms; Colonic Neoplasms; Rare Diseases; Carcinoma, Transitional Cell; Neoplasms Details
[89Zr]-Df-Trastuzumab Phase 1 Clinical University Of Alabama At Birmingham Solid tumours; Neoplasms; Breast Neoplasms Details
Runimotamab BTRC-4017A; RG-6194 Phase 1 Clinical F. Hoffmann-La Roche Ltd Solid tumours; Neoplasms Details
Sapitinib AZD-8931 Phase 2 Clinical Astrazeneca Pharmaceutical Co Ltd Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
Pertuzumab biosimilar(SL Pharma/Combio) Phase 1 Clinical Beijing Kangming Bio New Drug Development Co Ltd, Beijing Sl Pharmaceutical Co Ltd Inflammatory Breast Neoplasms; Breast Neoplasms; Metastatic breast cancer Details
FDA022 Antibody Drug Conjugate Phase 1 Clinical Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd Solid tumours; Neoplasms Details
HLX-22 AC-101; HLX-22 Phase 2 Clinical Shanghai Henlius Biotech Co Ltd Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
GQ-1005 GQ-1005; GQ1005 Phase 1 Clinical GeneQuantum Healthcare (Suzhou) Co Ltd Solid tumours; Neoplasms Details
anti-HER2 ADC (Pfizer) PF-06804103 Phase 2 Clinical Pfizer Inc Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms Details
YH-32367 ABL105; YH-32367 Phase 2 Clinical Abl Bio Inc Solid tumours; Stomach Neoplasms; Breast Neoplasms Details
EX-101 EX-101; EX101 Phase 1 Clinical Guangzhou ASM Biomedical Technology Co Ltd Solid tumours Details
XZP-5209 XZP-5209 Phase 1 Clinical Carcinoma, Non-Small-Cell Lung Details
Tarloxotinib Bromide PR-610; TH-4000; SN-33999 Phase 2 Clinical Threshold Solid tumours; Carcinoma, Non-Small-Cell Lung Details
DB-1303 DB-1303 Phase 2 Clinical Duality Biologics Co Ltd Solid tumours; Neoplasm Metastasis Details
JSKN-003 JSKN-003 Phase 1 Clinical Alphamab Oncology Solid tumours; Neoplasms Details
BB-1701 BB-1701 Phase 2 Clinical Baili Sikang Biomedicine (Hangzhou) Co Ltd Solid tumours; Carcinoma, Transitional Cell Details
ORM-5029 ORM-5029 Phase 1 Clinical Orum Therapeutics Inc Solid tumours; Breast Neoplasms Details
HER2/Neu GP2 vaccine(Greenwich LifeSciences Inc/NuGenerex Immuno Oncology) GLSI-100 Phase 3 Clinical Antigen Express Inc, Norwell Inc Breast Neoplasms Details
SAR-443216 SAR-443216 Phase 1 Clinical Sanofi Stomach Neoplasms; Neoplasms; Breast Neoplasms; Lung Neoplasms Details
Tesevatinib XL-647; KD-020; KD-019; EXEL-7647 Phase 2 Clinical Exelixis Inc Neoplasms; Glioblastoma; Breast Neoplasms; Brain Neoplasms; Polycystic Kidney, Autosomal Dominant; Brain metastases; Polycystic Kidney, Autosomal Recessive; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details
ZN-A-1041 ZN-A-1041 Phase 1 Clinical Suzhou Zanrong Pharmaceutical Technology Co Ltd Solid tumours; Neoplasms; Breast Neoplasms Details
DP-303c DP-303c; DP303c Phase 2 Clinical CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co Ltd Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Salivary Gland Neoplasms; Neoplasms; Breast Neoplasms; Metastatic breast cancer Details
BAY-2927088 BAY-2927088; BAY2927088 Phase 1 Clinical Bayer Healthcare Company Ltd, Bayer AG Carcinoma, Non-Small-Cell Lung Details
AIP-303 AIP-303 Phase 2 Clinical Advanced Imaging Projects Breast Neoplasms Details
Larotinib Mesylate Z-650 Phase 3 Clinical Guangdong Dongyangguang Pharmaceutical Co Ltd Solid tumours; Esophageal Neoplasms; Pancreatic Neoplasms; Esophageal Squamous Cell Carcinoma Details
Sunvozertinib DZD-9008 Phase 2 Clinical Dizal (Jiangsu) Pharmaceutical Co Ltd Lymphoma, B-Cell; Lymphoma, Non-Hodgkin; Carcinoma, Non-Small-Cell Lung Details
KSP-910638-G KSP-910638G; KSP-910638-G Phase 1 Clinical University Of Michigan Gastrointestinal Neoplasms Details
TAS-2940 TAS-2940 Phase 1 Clinical Taiho Oncology Inc Solid tumours; Glioblastoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
99mTc-HE3-G3 99mTc-HE3-G3; 99-mTc-HE-3-G-3; 99m-Tc-HE-3-G-3; 99mTc-(HE)3-G3 Phase 1 Clinical Tomsk National Research Medical Center Of The Russian Academy Of Sciences Solid tumours; Breast Neoplasms Details
99mTc-MIRC213 99-mTc-MIRC-213 Phase 1 Clinical Peking Union Medical College Hospital Breast Neoplasms Details
99mTc-MIRC208 Clinical Beijing Cancer Hospital Neoplasms Details
Gancotamab MM-302 Phase 2 Clinical Merrimack Pharmaceuticals Inc Ovarian Neoplasms; Breast Neoplasms Details
FCN-411 FCN-411 Phase 2 Clinical Shanghai Fosun Pharmaceutical (Group) Co Ltd Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Pirotinib Hydrochloride KBP-5209 Phase 2 Clinical Shandong Xuanzhu Pharmaceutical Technology Co Ltd Solid tumours; Neoplasms; Breast Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Trastuzumab biosimilar (Alteogen) ALT-L2; ALT-02; QL-1701; ALT-LS2 Phase 3 Clinical Alteogen Inc Stomach Neoplasms; Esophageal Neoplasms; Breast Neoplasms Details
ARV-471 ARV-471; PF-07850327 Phase 2 Clinical Arvinas Inc Breast Neoplasms Details
Varlitinib Ditosylate QBT-01; ARRY-543; SPS-4370; ASLAN-001; ARRY-334543 Phase 2 Clinical Array Biopharma Biliary Tract Neoplasms; Solid tumours; Stomach Neoplasms; Neoplasms; Pancreatic Neoplasms; Cholangiocarcinoma; Breast Neoplasms; Bile Duct Neoplasms Details
SHR-A1811 SHR-A1811 Phase 3 Clinical Jiangsu Hengrui Medicine Co Ltd, Suzhou Suncadia Biopharmaceuticals Co Ltd, Shanghai Hengrui Pharmaceutical Co Ltd Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Metastatic breast cancer; HR-positive breast cancer; Carcinoma, Non-Small-Cell Lung Details
[18F]GE-226 ABY-002; ABY-025; ABY-0125; 68GaABY025; GE-226; [68Ga]-ABY-025; GE-226-[18F]; [111]In-ABY-025; ABY-025-[68Ga]; ABY-025-[111In]; Gallium-68-ABY-025; Indium-111-ABY-025; Fluorine-18-GE-226 Phase 3 Clinical Affibody Ab Breast Neoplasms Details
ACE-1702 ACE-1702 Phase 1 Clinical Acepodia Taiwan Subsidiary Solid tumours; Stomach Neoplasms; Metastatic breast cancer; Neoplasm Metastasis Details
GQ-1001 GQ-1001 Phase 2 Clinical GeneQuantum Healthcare (Suzhou) Co Ltd Solid tumours; Breast Neoplasms; Metastatic breast cancer Details
IAH-0968 IAH-0968; IAH0968 Phase 2 Clinical Shenghe (China) Biopharmaceutical Co Ltd Solid tumours; Biliary Tract Neoplasms; Colorectal Neoplasms Details
Pertuzumab biosimilar (Shanghai Henlius Biotech) HLX-11 Phase 3 Clinical Shanghai Henlius Biotech Co Ltd Breast Neoplasms; Metastatic breast cancer Details
Zanidatamab zovodotin ZW-49 Phase 1 Clinical Zymeworks Inc Neoplasms Details
XMT-2056 XMT-2056 Phase 1 Clinical Mersana Therapeutics Inc Stomach Neoplasms; Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Zenocutuzumab MCLA-128 Phase 2 Clinical Merus Nv Solid tumours; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Anbenitamab KN-026 Phase 3 Clinical Suzhou Alphamab Co Ltd Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Breast Neoplasms; Lymphoma; Gastrointestinal Neoplasms Details
Coprelotamab GB-221 Phase 3 Clinical Genor Biopharma Co Ltd Breast Neoplasms Details
Trastuzumab monomethyl auristatin F FS-1502; LCB14-0110; LCB-14-0110 Phase 2 Clinical Legochembio Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Trastuzumab biosimilar (Hanwha Biologics) HD-201 Phase 3 Clinical Hanwha Biologics Kidney Neoplasms; Breast Neoplasms Details
Fidasimtamab IBI-315 Phase 1 Clinical Hanmi Pharmaceutical Co Ltd, Innovent Biologics(Suzhou) Co Ltd Solid tumours; Neoplasms Details
ARX-788 ARX-788; NCB-001 Phase 3 Clinical Ambrx Inc Solid tumours; Stomach Neoplasms; Esophageal Neoplasms; Neoplasms; Breast Neoplasms; Bile Duct Neoplasms Details
Zanidatamab ZW-25 Phase 3 Clinical Zymeworks Inc Biliary Tract Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Breast Neoplasms; Bile Duct Neoplasms; Esophageal adenocarcinoma; Endometrial Neoplasms; Carcinosarcoma; Gastrointestinal Neoplasms Details
DF-1001 DF-1001 Phase 2 Clinical Dragonfly Therapeutics Llc Solid tumours Details

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