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Frizzled-10

概要

Name:Frizzled-10
Target Synonym:Frizzled Class Receptor 10,FZD10,Frizzled 10, Seven Transmembrane Spanning Receptor,Frizzled Family Receptor 10,HFz10,FzE7,Frizzled (Drosophila) Homolog 10,Frizzled Homolog 10 (Drosophila),Frizzled Homolog 10,CD350 Antigen,Frizzled-10,CD350,Fz-10,Fz10
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

製品リスト製品比較と製品注文

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製造番号 種類 製品説明 構造 純度 特徴
FRD-H52H3 Human Human Frizzled-10 / FZD10 Protein, His Tag (MALS verified)
FRD-H52H3-structure
FRD-H52H3-sds
ACRO Quality

生物活性データの一部

FRD-H52H3-MALS-HPLC
Human Frizzled-10, His Tag (Cat. No. ) MALS images

The purity of Human Frizzled-10, His Tag (Cat. No. FRD-H52H3) is more than 90% and the molecular weight of this protein is around 18-25 kDa verified by SEC-MALS.

  • Background
    Frizzled-10 (FZD10) is also known as FzE7 or CD350, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD10 contains one FZ (frizzled) domain. FZD10 protein is a cell surface receptor, which is activated by Wnt proteins and involved in the regulation of cellular function. FZD10 interacts with WNT7B and MYOC.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Synonym Name

Fz-10, FZD10, hFz10, FzE7, CD350

Background

Frizzled-10 (FZD10) is also known as FzE7 or CD350, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD10 contains one FZ (frizzled) domain. FZD10 protein is a cell surface receptor, which is activated by Wnt proteins and involved in the regulation of cellular function. FZD10 interacts with WNT7B and MYOC.

Clinical and Translational Updates

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Tabituximab barzuxetan indium In-111 OTSA 101 DTPA-111In; 111IN-OTSA-101 Oncotherapy Science, Inc Details
Tabituximab barzuxetan indium In-111 OTSA 101 DTPA-111In; 111IN-OTSA-101 Oncotherapy Science, Inc Details

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