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Your Position: ホーム > Antibody > PD-L1 > HCS-S240

Recombinant Monoclonal Anti-PD-L1 Antibody, Rabbit (5D3)

  • Background
    PD-L1, is a ligand that binds with the receptor PD1, commonly found on T-cells, and acts to block T-cell activation. PD1 expression has been observed in a variety of cancers including melanoma and non-small cell lung cancer. The interaction of PD1/PDL1 is hypothesized to be a possible mechanism for the tumor to escape immune response. A number of checkpoint blockade inhibitors including pembrolizumab and nivolumab have been developed that target the PD1/PDL1 interaction in order to allow T-cells to recognize tumor cells without being deactivated by the tumor.
  • Host Species

    Rabbit

  • Clone

    5D3

  • Application

    IHC

  • Property
    1:1000
  • State
    Liquid
  • Positive Control
    Human Tonsil Tissues
  • Clonality
    Monoclonal
  • Synonym
    CD274, PD-L1
  • Research Field
    Cancer Drug Targets
  • Source
    Rabbit
  • Isotype
    IgG
  • Storage
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Typical Data
Control Sample
 PD-L1 CONTROL SAMPLE

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HCS-S240 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Cancer Sample
 PD-L1 CANCER SAMPLE PD-L1 CANCER SAMPLE PD-L1 CANCER SAMPLE

Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HCS-S240 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

  • Clinical and Translational Updates

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ETD of in-stock products: 4 business days

価格(USD) : 250.00

価格(USD) : 1000.00

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